Amazon One Medical is launching an agentic health AI assistant for use in the One Medical app.
The assistant seems to be drawing on the appeal of using a consumer chatbot for round-the-clock access to health information, and vying for consumer trust in the space. Amazon One Medical differentiates itself from generic health information tools by touting the Health AI agent’s connection to the Amazon One Medical ecosystem.
The tool, developed in conjunction with One Medical’s clinical leadership, offers 24/7 access to health information, whether it be questions about symptoms, a patient’s medications or dietary advice.
If needed, the Health AI agent can connect patients to their primary care providers for virtual visits or in-person care. It understands the unique patient’s medical history without the need to upload records from disparate sources, and it can manage medications, according to the company. Conversations with the Health AI assistant are not automatically added to an individual's medical record, the company said.
Amazon One Medical stressed that the new capability will not replace providers but work in tandem with them. The technology is HIPAA-compliant and has robust data privacy protections, according to a press release from the company. Amazon One Medical said it does not sell data to third parties.
OpenAI has long touted the use of ChatGPT for consumers to understand their health information.
Among the more than 800 million regular ChatGPT users, one in four submits a healthcare-related prompt every week, according to OpenAI. More than 40 million turn to ChatGPT every day with healthcare questions.
While Amazon One Medical’s Health AI agent is able to take action in a way that ChatGPT cannot, it also touts the agent’s more generic capabilities, like answering wellness questions, explaining health information and providing guidance on symptoms, conditions and potential treatments.
A chatbot’s ability to explain health questions or decipher lab results is perhaps its main draw for consumers. Sam Altman, CEO of OpenAI, touted GPT-5’s ability to help a cancer patient better understand their medical records, testing and course of treatment.
Amazon One Medical’s Health AI agent can also answer more complex medical questions and draw from the patient’s medical history, including lab results and vaccination records.
It can guide patients to the right level of care based on the symptoms they’re experiencing and schedule an urgent care visit or a visit with their primary care provider. It can determine whether a patient is better off seeing their provider in person—like if they have recurring urinary tract infections.
“The U.S. healthcare experience is fragmented, with each provider seeing only parts of your health puzzle,” Neil Lindsay, senior vice president of Amazon Health Services, said in a statement. “Health AI in the One Medical app brings together all the pieces of your personal health information to give you a more complete picture—helping you understand your health, and supporting you in getting the care you need to get and stay well. Health AI makes getting health care easier and more convenient, so patients can focus on what matters most: their health.”
Amazon One Medical's new AI chatbot comes as Anthropic and OpenAI recently unveiled new AI tools for healthcare organizations and patients. OpenAI's ChatGPT Health connect users' health records with the chatbot.
The rise of AI chatbots in healthcare marks a major shift in how patients are getting medical guidance. Consumers want 24/7 access to simple answers, personalized for their needs, noted Arielle Trzcinski, principal analyst at Forrester.
“Our data has shown a sharp rise in consumer openness to AI in health contexts, especially when it delivers meaningful personalization and reduces effort. From 2024 to 2025, Gen Z and Millennials’ interest in AI symptom checkers rose from 26% to 39%. We’re seeing exponential growth in adoption of these emerging technologies by consumers. It is essential that the industry delivers tools that ensure responsible, ethical use of data, and cocreate value," Trzcinski said.
"Consumers are more willing to adopt AI when it demonstrably helps them make better decisions—not just gives generic information. AI grounded in a person’s own data puts them in control and delivers insights built for them, not just for someone ‘like’ them," she said.